Issue 8, 2012
From the journal:

Analytical Methods

A highly sensitive resonance scattering based sensor using unmodified gold nanoparticles for daunomycin detection in aqueous solution†

Lan He,abcd   Wenting Zhi,bcd   Yuangen Wu,bcd   Shenshan Zhan,bcd   Faze Wang,bcd   Haibo Xingbcd  and  Pei Zhou*bcd  

* Corresponding authors

a School of Environmental Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, P.R. China

b School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, P.R. China

c Key Laboratory of Urban Agriculture (South) of Ministry of Agriculture, Shanghai 200240, P.R. China

d Bor S. Luh Food Safety Research Center, Shanghai 200240, P.R. China

Abstract

A sensitive sensor for detection of daunomycin (DNR) was developed by using free-labeled gold nanoparticles (AuNPs) and DNR aptamer. In the absence of DNR, free aptamer could absorb onto the surface of AuNPs to prevent them from aggregating in high salt solution. In the presence of DNR, the aptamer was firstly exhausted due to the formation of a DNR/aptamer complex, which lead to the remarkable change of resonance scattering (RS) intensity at 550 nm. Such sensor showed high selectivity and a detection limit of 17.1 nM. Based on the advantage of the sensor, the proposed sensing method is believed to be implemented to the on-site and real-time DNR detection in food safety and other applications.

Graphical abstract: A highly sensitive resonance scattering based sensor using unmodified gold nanoparticles for daunomycin detection in aqueous solution

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Article information

DOI
https://doi.org/10.1039/C2AY25596K
Article type
Paper
Submitted
08 Jun 2012
Accepted
08 Jun 2012
First published
13 Jun 2012

Anal. Methods, 2012,4, 2266-2271

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A highly sensitive resonance scattering based sensor using unmodified gold nanoparticles for daunomycin detection in aqueous solution

L. He, W. Zhi, Y. Wu, S. Zhan, F. Wang, H. Xing and P. Zhou, Anal. Methods, 2012, 4, 2266 DOI: 10.1039/C2AY25596K

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