Jump to main content
Jump to site search

Issue 8, 2012
Previous Article Next Article

Determination of enantiomer compositions of propranolol enantiomers by chiral ionic liquid as a chiral selector and the UV-assisted spectrophotometric method

Author affiliations

Abstract

Many chiral selectors have been used for recognition of enantiomeric compounds but their synthesis involves time-consuming and expensive multistep-processes with almost not optically pure products. In this paper, 1-butyl-3-methylimidazolium (T-4)-bis[(αS)-α-(hydroxy-O) benzeneacetato-κO] borate, a chiral ionic liquid which can be easily synthesized, was first used as a chiral selector in solution. The enantiomer compositions of propranolol hydrochloride were determined by using this chiral selector and the spectrophotometric method. The data of UV spectra showed that S-propranolol hydrochloride could be recognized in the mixture of the enantiomers with a total concentration of 1.50 × 10−4 M.

Graphical abstract: Determination of enantiomer compositions of propranolol enantiomers by chiral ionic liquid as a chiral selector and the UV-assisted spectrophotometric method

Back to tab navigation

Publication details

The article was received on 14 Feb 2012, accepted on 08 Jun 2012 and first published on 13 Jun 2012


Article type: Paper
DOI: 10.1039/C2AY25161B
Anal. Methods, 2012,4, 2283-2287

  •   Request permissions

    Determination of enantiomer compositions of propranolol enantiomers by chiral ionic liquid as a chiral selector and the UV-assisted spectrophotometric method

    G. Absalan, Y. Alipour, Z. Rezaei and M. Akhond, Anal. Methods, 2012, 4, 2283
    DOI: 10.1039/C2AY25161B

Search articles by author

Spotlight

Advertisements