Issue 6, 2012
From the journal:

Analytical Methods

Study on the interaction behavior of catalase with cephalosporins by chemiluminescence with flow injection analysis†‡

Donghua Chen,a   Zhuming Wang,ab   Yun Zhang,a   Xunyu Xionga  and  Zhenghua Song*a  

* Corresponding authors

a Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry & Material Science, Northwest University, Xi'an, China
E-mail: songzhenghua@hotmail.com
Fax: (+86)029-88302604
Tel: (+86)029-88303798

b Key Laboratory of Western Mineral Resources and Geological Engineering Ministry of Education, College of Earth Sciences and Land Resources, Chang'an University, Xi'an, China

Abstract

The interaction behavior of catalase with cephalosporins was first studied using luminol as luminescence probe. By chemiluminescence model of protein–drug interaction in flow injection system, the binding parameters of catalase with cephalosporins were obtained, giving the binding ability of cephalosporins to catalase and the thermodynamic parameters of catalase/cephalosporins association process.

Graphical abstract: Study on the interaction behavior of catalase with cephalosporins by chemiluminescence with flow injection analysis

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Article information

DOI
https://doi.org/10.1039/C2AY05642A
Article type
Communication
Submitted
05 Oct 2011
Accepted
18 Nov 2011
First published
19 Dec 2011

Anal. Methods, 2012,4, 1485-1487

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Study on the interaction behavior of catalase with cephalosporins by chemiluminescence with flow injection analysis

D. Chen, Z. Wang, Y. Zhang, X. Xiong and Z. Song, Anal. Methods, 2012, 4, 1485 DOI: 10.1039/C2AY05642A

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