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Issue 1, 2012
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Fabrication of a sensor for simultaneous determination of norepinephrine, acetaminophen and tryptophan using a modified carbon nanotube paste electrode

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Abstract

A carbon paste electrode (CPE) was modified by incorporation of carbon nanotubes and ferrocene (FC) and studied in pH 7.0 phosphate buffer solution (PBS) by cyclic voltammetry (CV). The modified electrode showed an excellent electrocatalytic effect on the oxidation of norepinephrine (NE). In PBS of pH 7.0, the oxidation current increased linearly with concentration of NE from 0.47 to 500.0 μmol L−1. The detection limit (3σ) obtained by differential pulse voltammetry (DPV) was 0.21 μmol L−1. Then the modified electrode was used to determine NE in an excess of acetaminophen (AC) and tryptophan (TRP) by DPV. Finally, this method was used for the determination of NE, AC and TRP in some real samples.

Graphical abstract: Fabrication of a sensor for simultaneous determination of norepinephrine, acetaminophen and tryptophan using a modified carbon nanotube paste electrode

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Publication details

The article was received on 14 Aug 2011, accepted on 13 Oct 2011 and first published on 28 Nov 2011


Article type: Paper
DOI: 10.1039/C1AY05503H
Anal. Methods, 2012,4, 259-264

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    Fabrication of a sensor for simultaneous determination of norepinephrine, acetaminophen and tryptophan using a modified carbon nanotube paste electrode

    M. R. Akhgar, H. Beitollahi, M. Salari, H. Karimi-Maleh and H. Zamani, Anal. Methods, 2012, 4, 259
    DOI: 10.1039/C1AY05503H

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