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Issue 10, 2010
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Energy transfer with gold nanoparticles for analytical applications in the fields of biochemical and pharmaceutical sciences

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Abstract

Gold nanoparticles (AuNPs) are the most interesting nanomaterials for analytical purposes owing to their unique optical and electrochemical properties resulting from the localized surface plasmon resonance (LSPR) of the electrons, displaying strong absorption and scattering of light from visible to near-infrared region by tuning the particles sizes and shapes. In fluorescence resonance energy transfer (FRET) process, AuNPs have been identified to act as excellent acceptors to replace traditional organic quenchers. Starting from quenching advantages of AuNPs in FRET system and energy transfer mechanism of donor to AuNPs, herein we try to summarize and discuss typical AuNPs based FRET methods in terms of DNA hybridizations, immunoreactions, specific molecular bindings or adsorptions, and provide their analytical applications in biochemical and pharmaceutical analysis.

Graphical abstract: Energy transfer with gold nanoparticles for analytical applications in the fields of biochemical and pharmaceutical sciences

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Publication details

The article was received on 16 Jul 2010, accepted on 03 Aug 2010 and first published on 17 Sep 2010


Article type: Minireview
DOI: 10.1039/C0AY00452A
Anal. Methods, 2010,2, 1439-1447

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    Energy transfer with gold nanoparticles for analytical applications in the fields of biochemical and pharmaceutical sciences

    J. Ling and C. Z. Huang, Anal. Methods, 2010, 2, 1439
    DOI: 10.1039/C0AY00452A

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