An illustration of the physical robustness of silica monolithic rod columns

Abstract

A commercial silica monolithic rod column (100 × 4.6 mm) was cut into smaller sections using a saw. Each time a section was cut from the column, the performance of the remaining intact monolith was retested. No significant change in the performance of the bed was recorded following the removal of 40 mm of the column in three separate cut sections. The work illustrates that monoliths are extremely robust and that they can be remodelled to different lengths if required, or a blocked section of the column (i.e. inlet) could be removed in much the same manner as for GC columns.