Jump to main content
Jump to site search

Issue 19, 2020
Previous Article Next Article

Surface-enhanced Raman spectroscopy (SERS) for detection of VX and HD in the gas phase using a hand-held Raman spectrometer

Author affiliations

Abstract

A sensitive surface-enhanced Raman spectroscopy (SERS) substrate was developed to enable hand-held Raman spectrometers to detect gas-phase VX and HD. The substrate comprised Au nanoparticles modified onto quartz fibres. Limits of detection (LOD) of 0.008 μg L−1 and 0.054 μg L−1 were achieved for VX and HD, respectively. Gas-phase experiments were performed using a homemade gas-phase flow system inside a climatic chamber at 25 °C and 50% relative humidity. Preliminary experiments were conducted using VX and HD in solution with Au and Ag nanoparticle colloidal suspensions. We developed and optimized several SERS methods for detection of VX and HD in solution. Gold nanoparticles were optimal for detection of VX and HD and were modified onto quartz fibres for gas-phase detection. The LODs for HD and VX detection in solution were 1.8 × 10−3 μg mL−1 (1.1 × 10−8 M) and 2.5 × 10−3 μg mL−1 (9.3 × 10−9 M), respectively. This study demonstrates that integration of SERS substrates with hand-held Raman spectrometers expands the applicability of Raman technology to homeland security, as reflected by increased sensitivity and gas-phase detection capabilities.

Graphical abstract: Surface-enhanced Raman spectroscopy (SERS) for detection of VX and HD in the gas phase using a hand-held Raman spectrometer

Back to tab navigation

Supplementary files

Article information


Submitted
11 Jun 2020
Accepted
20 Jul 2020
First published
20 Jul 2020

Analyst, 2020,145, 6334-6341
Article type
Paper

Surface-enhanced Raman spectroscopy (SERS) for detection of VX and HD in the gas phase using a hand-held Raman spectrometer

V. Heleg-Shabtai, H. Sharabi, A. Zaltsman, I. Ron and A. Pevzner, Analyst, 2020, 145, 6334
DOI: 10.1039/D0AN01170C

Social activity

Search articles by author

Spotlight

Advertisements