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Issue 10, 2020
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Application of DNA nanodevices for biosensing

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Abstract

Deoxyribonucleic acid (DNA), the carrier of genetic information in living life, is an essential biomacromolecule in almost all living systems. DNA has advantages including, programmability, predictability, high rigidity, and stability. Through self-assembly or combination with other nanomaterials (such as gold nanoparticles, graphene oxides, quantum dots, and polymers), DNA can be applied to construct specific, stable, biocompatible, and functional nanodevices. DNA nanodevices have made greater contributions in a plethora of fields. In this review, we discuss the recent progress of DNA nanodevices in molecular detection and analysis. Meanwhile, we prospect the development of various DNA devices in biological analysis, clinical diagnosis and biomedical research.

Graphical abstract: Application of DNA nanodevices for biosensing

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Article information


Submitted
21 Jan 2020
Accepted
31 Mar 2020
First published
02 Apr 2020

Analyst, 2020,145, 3481-3489
Article type
Minireview

Application of DNA nanodevices for biosensing

S. Yu, T. Chen, Q. Zhang, M. Zhou and X. Zhu, Analyst, 2020, 145, 3481
DOI: 10.1039/D0AN00159G

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