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Issue 4, 2019
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Gold nanoparticle based fluorescent oligonucleotide probes for imaging and therapy in living systems

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Abstract

Gold nanoparticles (AuNPs) with unique physical and chemical properties have become an integral part of research in nanoscience. In particular, the development of AuNP-based fluorescent oligonucleotide (AuFO) probes targeted at living systems through fluorescence are drawing increasing attention and have become a current hot topic in biomedical research. This review describes recent advances and developments in the use of AuFO probes from their preparation and features that allow the desired intracellular delivery to their applications in cellular imaging and drug delivery in living systems.

Graphical abstract: Gold nanoparticle based fluorescent oligonucleotide probes for imaging and therapy in living systems

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Publication details

The article was received on 27 Oct 2018, accepted on 12 Dec 2018 and first published on 13 Dec 2018


Article type: Critical Review
DOI: 10.1039/C8AN02070A
Analyst, 2019,144, 1052-1072

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    Gold nanoparticle based fluorescent oligonucleotide probes for imaging and therapy in living systems

    Y. Yang, S. Zhong, K. Wang and J. Huang, Analyst, 2019, 144, 1052
    DOI: 10.1039/C8AN02070A

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