Issue 13, 2016
From the journal:

Analyst

Graphene oxide–peptide nanoassembly as a general approach for monitoring the activity of histone deacetylases†

Ping Liang,a   Qing Li,*a   Zhan Wu,a   Jian-Hui Jiang*a  and  Ru-Qin Yua  

* Corresponding authors

a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China
E-mail: jianhuijiang@hnu.edu.cn, liqing880523@hnu.edu.cn
Fax: +86-731-88821916
Tel: +86-731-88821916

Abstract

A novel fluorescent sensor using graphene oxide (GO)–peptide nanoassembly is developed for histone deacetylases (HDACs) based on deacetylation mediated cleavage of substrate peptides, which provides a simple, cost-effective platform for monitoring the activity of HDACs.

Graphical abstract: Graphene oxide–peptide nanoassembly as a general approach for monitoring the activity of histone deacetylases

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Article information

DOI
https://doi.org/10.1039/C6AN00902F
Article type
Communication
Submitted
18 Apr 2016
Accepted
12 May 2016
First published
12 May 2016

Analyst, 2016,141, 3989-3992

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Graphene oxide–peptide nanoassembly as a general approach for monitoring the activity of histone deacetylases

P. Liang, Q. Li, Z. Wu, J. Jiang and R. Yu, Analyst, 2016, 141, 3989 DOI: 10.1039/C6AN00902F

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