Issue 7, 2016
From the journal:

Analyst

Electrochemical redox signaling of hemoglobin in human whole blood and its relevance to anemia and thalassemia diagnosis†

Khairunnisa Amreena  and  Annamalai Senthil Kumar ORCID logo *a  

* Corresponding authors

a Environmental and Analytical Chemistry Division, School of Advanced Sciences, Vellore Institute of Technology University, Vellore-632 014, India
E-mail: askumarchem@yahoo.com

Abstract

A highly redox active human whole blood–carbon nanomaterial modified electrode has been developed, which showed a redox peak (Image ID:c5an02646f-t1.gifvs. Ag/AgCl) similar to that of hemoglobin (Image ID:c5an02646f-t2.gifvs. Ag/AgCl) in red blood cells. Clinical relevance of this for direct electrochemical analysis of blood hemoglobin content (anemia) and thalassemia disease diagnosis was demonstrated.

Graphical abstract: Electrochemical redox signaling of hemoglobin in human whole blood and its relevance to anemia and thalassemia diagnosis

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Article information

DOI
https://doi.org/10.1039/C5AN02646F
Article type
Communication
Submitted
25 Dec 2015
Accepted
15 Feb 2016
First published
15 Feb 2016

Analyst, 2016,141, 2145-2149

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Electrochemical redox signaling of hemoglobin in human whole blood and its relevance to anemia and thalassemia diagnosis

K. Amreen and A. S. Kumar, Analyst, 2016, 141, 2145 DOI: 10.1039/C5AN02646F

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