Issue 5, 2016
From the journal:

Analyst

Rapid discrimination of bacteria using a miniature mass spectrometer†

Christopher J. Pulliam,‡a   Pu Wei,‡a   Dalton T. Snyder,a   Xiao Wang,b   Zheng Ouyang,b   Rafal M. Pielakc  and  R. Graham Cooks*a  

* Corresponding authors

a Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA
E-mail: cooks@purdue.edu

b Department of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA

c L'Oreal California Research Center, San Francisco, CA, USA

Abstract

Bacteria colonies were analyzed using paper spray ionization coupled with a portable mass spectrometer. The spectra were averaged and processed using multivariate analysis to discriminate between different species of bacteria based on their unique phospholipid profiles. Full scan mass spectra and product ion MS/MS data were compared to those recorded using a benchtop linear ion trap mass spectrometer.

Graphical abstract: Rapid discrimination of bacteria using a miniature mass spectrometer

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Article information

DOI
https://doi.org/10.1039/C5AN02575C
Article type
Communication
Submitted
15 Dec 2015
Accepted
30 Jan 2016
First published
04 Feb 2016

Analyst, 2016,141, 1633-1636

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Rapid discrimination of bacteria using a miniature mass spectrometer

C. J. Pulliam, P. Wei, D. T. Snyder, X. Wang, Z. Ouyang, R. M. Pielak and R. Graham Cooks, Analyst, 2016, 141, 1633 DOI: 10.1039/C5AN02575C

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