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Issue 1, 2016
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A highly sensitive strategy for base excision repair enzyme activity detection based on graphene oxide mediated fluorescence quenching and hybridization chain reaction

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Abstract

A novel fluorescent nanosensor has been developed by combining super fluorescence quenching ability of graphene oxide and hybridization chain reaction amplification, which enables highly sensitive detection of base excision repair enzyme activity with a wide dynamic range from 0.0001 to 100 U mL−1 and a detection limit of 0.00006 U mL−1.

Graphical abstract: A highly sensitive strategy for base excision repair enzyme activity detection based on graphene oxide mediated fluorescence quenching and hybridization chain reaction

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Article information


Submitted
30 Oct 2015
Accepted
17 Nov 2015
First published
18 Nov 2015

Analyst, 2016,141, 96-99
Article type
Communication
Author version available

A highly sensitive strategy for base excision repair enzyme activity detection based on graphene oxide mediated fluorescence quenching and hybridization chain reaction

Q. Xi, J. Li, W. Du, R. Yu and J. Jiang, Analyst, 2016, 141, 96
DOI: 10.1039/C5AN02255J

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