Jump to main content
Jump to site search

Issue 2, 2016
Previous Article Next Article

Cancer screening via infrared spectral cytopathology (SCP): results for the upper respiratory and digestive tracts

Author affiliations

Abstract

Instrumental advances in infrared micro-spectroscopy have made possible the observation of individual human cells and even subcellular structures. The observed spectra represent a snapshot of the biochemical composition of a cell; this composition varies subtly but reproducibly with cellular effects such as progression through the cell cycle, cell maturation and differentiation, and disease. The aim of this summary is to provide a synopsis of the progress achieved in infrared spectral cytopathology (SCP) – the combination of infrared micro-spectroscopy and multivariate methods of analysis – for the detection of abnormalities in exfoliated human cells of the upper respiratory and digestive tract, namely the oral and nasopharyngeal cavities, and the esophagus.

Graphical abstract: Cancer screening via infrared spectral cytopathology (SCP): results for the upper respiratory and digestive tracts

Back to tab navigation

Article information


Submitted
26 Aug 2015
Accepted
24 Sep 2015
First published
28 Sep 2015

Analyst, 2016,141, 416-428
Article type
Minireview

Cancer screening via infrared spectral cytopathology (SCP): results for the upper respiratory and digestive tracts

M. Diem, M. Miljković, B. Bird, A. I. Mazur, J. M. Schubert, D. Townsend, N. Laver, M. Almond and O. Old, Analyst, 2016, 141, 416
DOI: 10.1039/C5AN01751C

Social activity

Search articles by author

Spotlight

Advertisements