Issue 10, 2015
From the journal:

Analyst

A smart tailor-made G-clip reporter for sensitive detection of G-triplet-containing sequences†

Liang-Yuan Cai,a   Ji Nie,a   Yi-Wei Zhang,a   Fang-Ting Zhang,a   Ying-Lin Zhou*a  and  Xin-Xiang Zhang*a  

* Corresponding authors

a Beijing National Laboratory for Molecular Sciences (BNLMS), MOE Key Laboratory of Bioorganic Chemistry and Molecular Engineering, College of Chemistry, Peking University, Beijing 100871, China
E-mail: zhouyl@pku.edu.cn, zxx@pku.edu.cn
Fax: +86-10-62754112
Tel: +86-10-62754112

Abstract

Taking advantage of the intrinsic characteristics of G-triplet-containing sequences, a pioneering tailor-made clip-like reporter containing three-fourths of a G-quadruplex is established. The reporter can clip the G triplet in the target sequence through a recognition process to form a complete G-quadruplex structure.

Graphical abstract: A smart tailor-made G-clip reporter for sensitive detection of G-triplet-containing sequences

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Article information

DOI
https://doi.org/10.1039/C5AN00281H
Article type
Communication
Submitted
10 Feb 2015
Accepted
25 Mar 2015
First published
25 Mar 2015

Analyst, 2015,140, 3343-3346

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A smart tailor-made G-clip reporter for sensitive detection of G-triplet-containing sequences

L. Cai, J. Nie, Y. Zhang, F. Zhang, Y. Zhou and X. Zhang, Analyst, 2015, 140, 3343 DOI: 10.1039/C5AN00281H

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