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Issue 8, 2015
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Binary DNA hairpin-based colorimetric biochip for simultaneous detection of Pb2+ and Hg2+ in real-world samples

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Abstract

A microarray-format colorimetric biochip was constructed on plastic using two specially-designed DNA hairpin strands as binary probes and a binding-induced conformational switching strategy as the signal generation protocol. Coupled with single- or dual-color staining, we were able to simultaneously detect and quantitate the trace amounts of Pb2+ and Hg2+ in various real-world samples.

Graphical abstract: Binary DNA hairpin-based colorimetric biochip for simultaneous detection of Pb2+ and Hg2+ in real-world samples

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Article information


Submitted
20 Jan 2015
Accepted
30 Jan 2015
First published
30 Jan 2015

Analyst, 2015,140, 2608-2612
Article type
Communication
Author version available

Binary DNA hairpin-based colorimetric biochip for simultaneous detection of Pb2+ and Hg2+ in real-world samples

X. Shi, X. Gao, L. Zhang, Y. Li, L. Fan and H. Yu, Analyst, 2015, 140, 2608
DOI: 10.1039/C5AN00120J

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