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Issue 8, 2015
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Gold nanoparticle/polymer nanocomposite for highly sensitive drug–DNA interaction

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Abstract

The interaction of the anticancer drug mitomycin C (MC) and DNA immobilized on gold a nanoparticle/polyvinylferrocenium (AuNP/PVF+) coated electrode is presented. This is the first attempt to prepare a biocompatible nanoparticle/redox polymer composite in a one-step and easy electropolymerization procedure and then use the coated electrode for MC–DNA interaction. The prepared electrode exhibits high sensitivity for the investigation of drug–DNA interaction.

Graphical abstract: Gold nanoparticle/polymer nanocomposite for highly sensitive drug–DNA interaction

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Supplementary files

Article information


Submitted
11 Jan 2015
Accepted
23 Feb 2015
First published
24 Feb 2015

Analyst, 2015,140, 2876-2880
Article type
Paper
Author version available

Gold nanoparticle/polymer nanocomposite for highly sensitive drug–DNA interaction

F. Kuralay and A. Erdem, Analyst, 2015, 140, 2876
DOI: 10.1039/C5AN00061K

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