Issue 22, 2014
From the journal:

Analyst

Monodisperse sphere-on-sphere silica particles for fast HPLC separation of peptides and proteins†

Richard Hayes,a   Peter Myers,a   Tony Edgeb  and  Haifei Zhang*a  

* Corresponding authors

a Department of Chemistry, University of Liverpool, Liverpool, UK
E-mail: zhanghf@liv.ac.uk

b Thermo Fisher Scientific, Manor Park, Runcorn, UK

Abstract

Monodisperse sphere-on-sphere (SOS) silica particles are produced in a one-pot reaction, removing the need for time-consuming preparation and classification steps. Analysis of peptides and proteins using HPLC displays faster separation at lower operating pressure than commercially available fused core materials.

Graphical abstract: Monodisperse sphere-on-sphere silica particles for fast HPLC separation of peptides and proteins

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Article information

DOI
https://doi.org/10.1039/C4AN01428F
Article type
Communication
Submitted
04 Aug 2014
Accepted
12 Sep 2014
First published
12 Sep 2014

Analyst, 2014,139, 5674-5677

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Monodisperse sphere-on-sphere silica particles for fast HPLC separation of peptides and proteins

R. Hayes, P. Myers, T. Edge and H. Zhang, Analyst, 2014, 139, 5674 DOI: 10.1039/C4AN01428F

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