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Issue 22, 2014
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Rituximab–Au nanoprobes for simultaneous dark-field imaging and DAB staining of CD20 over-expressed on Raji cells

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Abstract

A novel dual-modal cell immunodetection method based on both dark-field imaging and catalysis functions of gold nanoparticles has been established, where the Rituximab–Au conjugates were used as nanoprobes to label and image specifically the CD20 overexpressed on the surface of malignant lymphoma cells of Raji with high affinity.

Graphical abstract: Rituximab–Au nanoprobes for simultaneous dark-field imaging and DAB staining of CD20 over-expressed on Raji cells

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Publication details

The article was received on 23 Jul 2014, accepted on 11 Sep 2014 and first published on 11 Sep 2014


Article type: Communication
DOI: 10.1039/C4AN01342E
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Citation: Analyst, 2014,139, 5660-5663

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    Rituximab–Au nanoprobes for simultaneous dark-field imaging and DAB staining of CD20 over-expressed on Raji cells

    L. Fan, D. Lou, Y. Zhang and N. Gu, Analyst, 2014, 139, 5660
    DOI: 10.1039/C4AN01342E

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