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Issue 22, 2014
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Rituximab–Au nanoprobes for simultaneous dark-field imaging and DAB staining of CD20 over-expressed on Raji cells

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Abstract

A novel dual-modal cell immunodetection method based on both dark-field imaging and catalysis functions of gold nanoparticles has been established, where the Rituximab–Au conjugates were used as nanoprobes to label and image specifically the CD20 overexpressed on the surface of malignant lymphoma cells of Raji with high affinity.

Graphical abstract: Rituximab–Au nanoprobes for simultaneous dark-field imaging and DAB staining of CD20 over-expressed on Raji cells

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Article information


Submitted
23 Jul 2014
Accepted
11 Sep 2014
First published
11 Sep 2014

Analyst, 2014,139, 5660-5663
Article type
Communication
Author version available

Rituximab–Au nanoprobes for simultaneous dark-field imaging and DAB staining of CD20 over-expressed on Raji cells

L. Fan, D. Lou, Y. Zhang and N. Gu, Analyst, 2014, 139, 5660
DOI: 10.1039/C4AN01342E

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