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Issue 19, 2014
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Signal amplification by a self-assembled biosensor system designed on the principle of dockerin–cohesin interactions in a cellulosome complex

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Abstract

To construct a self-assembled biosensor with signal amplification, a cellulosome system, comprising type I and type II dockerin–cohesin interactions with different specificities, from the anaerobic Clostridia bacterium was applied. The self-assembled biosensor was highly sensitive and achieved 128.1-fold increase in detection levels compared to the control.

Graphical abstract: Signal amplification by a self-assembled biosensor system designed on the principle of dockerin–cohesin interactions in a cellulosome complex

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Article information


Submitted
12 May 2014
Accepted
23 Jul 2014
First published
23 Jul 2014

Analyst, 2014,139, 4790-4793
Article type
Communication
Author version available

Signal amplification by a self-assembled biosensor system designed on the principle of dockerin–cohesin interactions in a cellulosome complex

J. E. Hyeon, D. H. Kang and S. O. Han, Analyst, 2014, 139, 4790
DOI: 10.1039/C4AN00856A

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