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Issue 11, 2014
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Single vs. two-photon microscopy for label free intrinsic tissue studies in the UV light region

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Abstract

Fibrillar distribution in the rat tail tendon and mice liver can be measured using optical methods. Two-photon excitation provides easy assessment of fibrotic collagen types I and II. Single photon deep ultraviolet (DUV) excitation imaging highlights all collagen types without discrimination. Their combination on the same tissue area provides a better overview of collagens in fibrillar diseases.

Graphical abstract: Single vs. two-photon microscopy for label free intrinsic tissue studies in the UV light region

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Publication details

The article was received on 27 Jan 2014, accepted on 20 Mar 2014 and first published on 21 Mar 2014


Article type: Communication
DOI: 10.1039/C4AN00203B
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Citation: Analyst, 2014,139, 2663-2667

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    Single vs. two-photon microscopy for label free intrinsic tissue studies in the UV light region

    V. Zubkovs, F. Jamme, S. Kascakova, F. Chiappini, F. Le Naour and M. Réfrégiers, Analyst, 2014, 139, 2663
    DOI: 10.1039/C4AN00203B

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