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Issue 11, 2014
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Glycan microarrays: new angles and new strategies

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Abstract

Carbohydrate microarrays, comprising hundreds to thousands of different glycan structures on solid surfaces in a spatially discrete pattern, are sensitive and versatile tools for the analysis of glycosylation changes in complex biological samples. Glycoarrays are also suitable for monitoring multiple molecular interactions with biomolecules where sugars are involved, offering a large variety of bioassay options. In this paper we review the most important glycan microarray types currently used with their main applications, and discuss some of the future challenges the technology faces.

Graphical abstract: Glycan microarrays: new angles and new strategies

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Publication details

The article was received on 12 Dec 2013, accepted on 24 Feb 2014 and first published on 25 Feb 2014


Article type: Tutorial Review
DOI: 10.1039/C3AN02289G
Citation: Analyst, 2014,139, 2650-2657

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    Glycan microarrays: new angles and new strategies

    B. Donczo, J. Kerekgyarto, Z. Szurmai and A. Guttman, Analyst, 2014, 139, 2650
    DOI: 10.1039/C3AN02289G

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