Issue 9, 2014

Convenient detection of the thiol functional group using H/D isotope sensitive Raman spectroscopy

Abstract

Raman spectra of several thiols (amino acids, peptides and organic) show that the C–S–H bending mode (βCSH) shifts from ∼850 cm−1 to ∼620 cm−1 on deuteration of the thiol proton by simply dissolving them in D2O and CD3OD where detection by 1H NMR is not possible. A nondestructive analytical tool for the detection of thiols in solid/neat and in solution is developed.

Graphical abstract: Convenient detection of the thiol functional group using H/D isotope sensitive Raman spectroscopy

Supplementary files

Article information

Article type
Communication
Submitted
22 Nov 2013
Accepted
14 Feb 2014
First published
14 Feb 2014

Analyst, 2014,139, 2118-2121

Author version available

Convenient detection of the thiol functional group using H/D isotope sensitive Raman spectroscopy

S. Bandyopadhyay and A. Dey, Analyst, 2014, 139, 2118 DOI: 10.1039/C3AN02166A

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