Jump to main content
Jump to site search

Issue 9, 2013
Previous Article Next Article

Smartphone-based detection of unlabeled DNA via electrochemical dissolution

Author affiliations

Abstract

We describe a novel approach that enables unlabeled biomolecules and chemical analytes to be detected using ordinary smartphone optics. Electrochemical reactivity of chromium, ordinarily considered detrimental, is harnessed here to generate a signature that can be easily seen by monitoring electrode dissolution under ordinary white-light illumination. The simplicity and robustness of this approach eliminates the need for labeling and/or pre-programming with specific receptors (e.g., oligonucleotide probes), making it feasible to greatly expand availability of a host of assays where detection complexity is a limiting constraint.

Graphical abstract: Smartphone-based detection of unlabeled DNA via electrochemical dissolution

Back to tab navigation

Supplementary files

Article information


Submitted
18 Dec 2012
Accepted
01 Mar 2013
First published
04 Mar 2013

Analyst, 2013,138, 2522-2526
Article type
Communication

Smartphone-based detection of unlabeled DNA via electrochemical dissolution

Y. Huang and V. M. Ugaz, Analyst, 2013, 138, 2522
DOI: 10.1039/C3AN36875K

Social activity

Search articles by author

Spotlight

Advertisements