Issue 5, 2013
From the journal:

Analyst

Luminescent silver nanoclusters anchored by oligonucleotides detect human telomerase ribonucleic acid template†

Yueteng Wei,a   Ru Liu,a   Zhipeng Sun,a   Yaling Wang,a   Yanyan Cui,a   Yuliang Zhao,a   Zhifang Caia  and  Xueyun Gao*a  

* Corresponding authors

a CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, People's Republic China
E-mail: gaoxy@ihep.ac.cn

Abstract

Luminescent silver nanoclusters were anchored by designed oligonucleotides. After hybridizing with human telomerase RNA template, the luminescence of the cluster decreased linearly with respect to the concentration of the complementary strand (25–250 nM). The cluster is therefore a potential candidate for human telomerase detection.

Graphical abstract: Luminescent silver nanoclusters anchored by oligonucleotides detect human telomerase ribonucleic acid template

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Article information

DOI
https://doi.org/10.1039/C3AN36689H
Article type
Communication
Submitted
15 Nov 2012
Accepted
16 Jan 2013
First published
17 Jan 2013

Analyst, 2013,138, 1338-1341

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Luminescent silver nanoclusters anchored by oligonucleotides detect human telomerase ribonucleic acid template

Y. Wei, R. Liu, Z. Sun, Y. Wang, Y. Cui, Y. Zhao, Z. Cai and X. Gao, Analyst, 2013, 138, 1338 DOI: 10.1039/C3AN36689H

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