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Issue 23, 2013
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A novel and photostable pH probe for selectively staining nuclei in living cells

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Abstract

A novel pH probe based on hemi-cyanine was synthesized, which displays extremely large Stokes shift (122 nm) and good photostability. The probe responds to basic pH (pKa 8.32) with a colorimetric and fluorescence turn-on signal. Interestingly, the probe has good cell membrane permeability and could selectively stain nuclei in living cells.

Graphical abstract: A novel and photostable pH probe for selectively staining nuclei in living cells

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Article information


Submitted
02 Sep 2013
Accepted
02 Oct 2013
First published
03 Oct 2013

Analyst, 2013,138, 7083-7086
Article type
Communication

A novel and photostable pH probe for selectively staining nuclei in living cells

L. Zeng, N. Fan, J. Zha, X. Hu, B. Fu, C. Qin and L. Wang, Analyst, 2013, 138, 7083
DOI: 10.1039/C3AN01655B

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