Issue 17, 2013

Functionalized liposome purificationvia Liposome Extruder Purification (LEP)

Abstract

Liposome Extruder Purification (LEP) allows for the rapid purification of diverse liposome formulations using the same extrusion apparatus employed during liposome formation. The LEP process provides a means for purifying functionalized liposomes from non-conjugated drug or protein contaminants with >93% liposome recovery and >93% contaminant removal in a single step.

Graphical abstract: Functionalized liposome purification via Liposome Extruder Purification (LEP)

Supplementary files

Article information

Article type
Communication
Submitted
05 Apr 2013
Accepted
02 Jul 2013
First published
02 Jul 2013

Analyst, 2013,138, 4746-4751

Functionalized liposome purification via Liposome Extruder Purification (LEP)

N. J. Alves, W. Cusick, J. F. Stefanick, J. D. Ashley, M. W. Handlogten and B. Bilgicer, Analyst, 2013, 138, 4746 DOI: 10.1039/C3AN00680H

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