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Issue 10, 2013
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Extremely selective “turn-on” fluorescence detection of hypochlorite confirmed by proof-of-principle neurological studies via esterase action in living cells

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Abstract

Highly specific and sensitive fluorescence detection of hypochlorite in nonbiotic pure water (rapid “turn-on”, ∼400 fold, λem ∼ 560 nm) as well as in living neuronal cell cultures (neutral pH) involves oxidation of a 2-sulfide-2-benzoic acid pendent group in a new meso-thienyl-BODIPY donor–acceptor probe.

Graphical abstract: Extremely selective “turn-on” fluorescence detection of hypochlorite confirmed by proof-of-principle neurological studies via esterase action in living cells

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Article information


Submitted
09 Feb 2013
Accepted
25 Mar 2013
First published
26 Mar 2013

Analyst, 2013,138, 2829-2832
Article type
Communication

Extremely selective “turn-on” fluorescence detection of hypochlorite confirmed by proof-of-principle neurological studies via esterase action in living cells

A. P. Singh, O. G. Tsay, D. P. Murale, T. Jun, H. Liew, Y. Suh and D. G. Churchill, Analyst, 2013, 138, 2829
DOI: 10.1039/C3AN00297G

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