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Issue 3, 2013
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Colorimetric detection of UV light-induced single-strand DNA breaks using gold nanoparticles

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Abstract

We developed a colorimetric method to specifically detect single-strand DNA breaks using gold nanoparticles. In our assay, broken DNA cannot stabilize gold nanoparticles to prevent salt-induced aggregation as good as intact DNA can, and this effect can be easily observed with the naked eye as a red-to-purple color change.

Graphical abstract: Colorimetric detection of UV light-induced single-strand DNA breaks using gold nanoparticles

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The article was received on 10 Oct 2012, accepted on 05 Dec 2012 and first published on 05 Dec 2012


Article type: Communication
DOI: 10.1039/C2AN36458A
Analyst, 2013,138, 783-786

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    Colorimetric detection of UV light-induced single-strand DNA breaks using gold nanoparticles

    J. H. Kim, C. H. Chung and B. H. Chung, Analyst, 2013, 138, 783
    DOI: 10.1039/C2AN36458A

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