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Issue 1, 2013
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A simple method for the determination of enantiomeric composition of propranolol enantiomers

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Abstract

A simple method of room temperature phosphorescence is proposed for the determination of propranolol enantiomeric composition based on β-cyclodextrin as the chiral host and bromocyclohexane as the heavy atom. Enantiomeric complexes are formed upon binding of the propranolol enantiomer to β-cyclodextrin, and the sign of the resultant phosphorescence signals allows for the identity of the propranolol enantiomers configuration to be determined successfully.

Graphical abstract: A simple method for the determination of enantiomeric composition of propranolol enantiomers

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Article information


Submitted
24 Jul 2012
Accepted
30 Oct 2012
First published
31 Oct 2012

Analyst, 2013,138, 107-110
Article type
Communication

A simple method for the determination of enantiomeric composition of propranolol enantiomers

Y. Wei, H. Kang, Y. Ren, G. Qin, S. Shuang and C. Dong, Analyst, 2013, 138, 107
DOI: 10.1039/C2AN36003A

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