Visual detection of potassium by a cyanine dye supramolecular aggregate responsive to G-quadruplex motif transition

Hongxia Sun; Junfeng Xiang; Wei Gai; Qian Shang; Qian Li; Aijiao Guan; Qianfan Yang; Yan Liu; Yalin Tang; Guangzhi Xu

doi:10.1039/C2AN35944H

Visual detection of potassium by a cyanine dye supramolecular aggregate responsive to G-quadruplex motif transition†

Hongxia Sun,^ab Junfeng Xiang,^a Wei Gai,^ab Qian Shang,^a Qian Li,^a Aijiao Guan,^a Qianfan Yang,^a Yan Liu,^a Yalin Tang*^a and Guangzhi Xu^a

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^a National Laboratory for Molecular Sciences, Center for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry Chinese Academy of Sciences, Beijing 100190, P. R. China
E-mail: tangyl@iccas.ac.cn
Fax: +86 10 62522090
Tel: +86 10 82617304

^b Graduate University of the Chinese Academy of Sciences, Yuquan Road 19(A), Shijingshan District, Beijing 100049, P. R. China

Abstract

A supramolecular probe is designed for visual detection of potassium based on a novel cyanine dye aggregate recognizing the motif transition of telomeric G-quadruplexes under the Na⁺ background. The practical application for colorimetric measurement of urine potassium has been tested.

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Visual detection of potassium by a cyanine dye supramolecular aggregate responsive to G-quadruplex motif transition†

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Visual detection of potassium by a cyanine dye supramolecular aggregate responsive to G-quadruplex motif transition

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