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Issue 22, 2012
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A new strategy for imaging biomolecular events through interactions between liquid crystals and oil-in-water emulsions

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Abstract

In this study, we demonstrate a new strategy to image biomolecular events through interactions between liquid crystals (LCs) and oil-in-water emulsions. The optical response had a dark appearance when a nematic LC, 4-cyano-4′-pentylbiphenyl (5CB), is in contact with emulsion droplets of glyceryl trioleate (GT). In contrast, the optical response had a bright appearance when 5CB is in contact with GT emulsions decorated with surfactants such as sodium oleate. Since lipase can hydrolyze GT and produce oleic acid, the optical response also displays a bright appearance after 5CB has been in contact with a mixture of lipase and GT emulsions. These results indicate the feasibility of monitoring biomolecular events through interactions between LCs and oil-in-water emulsions.

Graphical abstract: A new strategy for imaging biomolecular events through interactions between liquid crystals and oil-in-water emulsions

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Publication details

The article was received on 10 May 2012, accepted on 15 Sep 2012 and first published on 18 Sep 2012


Article type: Communication
DOI: 10.1039/C2AN35607D
Analyst, 2012,137, 5204-5207

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    A new strategy for imaging biomolecular events through interactions between liquid crystals and oil-in-water emulsions

    Q. Hu and C. Jang, Analyst, 2012, 137, 5204
    DOI: 10.1039/C2AN35607D

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