Issue 14, 2012

Fluorogenic and chromogenic probe for rapid detection of a nerve agent simulant DCP

Abstract

A fluorogenic and visual probe was devised to detect diethyl chlorophosphate (DCP), a nerve agent simulant. The probe, N-(rhodamine B)-lactam-2-aminoethanol (RB-AE), undergoes oxazoline formation following phosphorylation in the presence of DCP, which gives rapid and clear fluorescence and color change in the assay solutions.

Graphical abstract: Fluorogenic and chromogenic probe for rapid detection of a nerve agent simulant DCP

Supplementary files

Article information

Article type
Communication
Submitted
30 Mar 2012
Accepted
11 May 2012
First published
14 May 2012

Analyst, 2012,137, 3224-3226

Fluorogenic and chromogenic probe for rapid detection of a nerve agent simulant DCP

W. Wu, J. Dong, X. Wang, J. Li, S. Sui, G. Chen, J. Liu and M. Zhang, Analyst, 2012, 137, 3224 DOI: 10.1039/C2AN35428D

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