A novel non-enzymatic glucose sensor modified with Fe2O3nanowire arrays

Abstract

Fe₂O₃ was generally considered to be biologically and electrochemically inert, and its electrocatalytic functionality has been rarely realized directly in the past. In this work, Fe₂O₃ nanowire arrays were synthesized and electrochemically characterized. The as prepared Fe₂O₃ nanomaterial was proved to be an ideal electrode material due to the intrinsic peroxidase-like catalytic activity. The Fe₂O₃ nanowire array modified glucose sensor exhibited excellent biocatalytic performance towards the oxidation of glucose with a response time of <6 s, a linear range between 0.015–8 mM, and sensitivity of 726.9 μA mM⁻¹cm⁻¹. Additionally, a high sensing selectivity towards glucose oxidation in the presence of ascorbic acid (AA) and dopamine (DA) has also been obtained at their maximum physiological concentrations, which makes the Fe₂O₃ nanomaterial promising for the development of effective electrochemical sensors for practical applications.