Issue 11, 2011
From the journal:

Analyst

Artificial-epitope mapping for CK-MB assay†

Dar-Fu Tai,*a   Yi-Fang Ho,a   Cheng-Hsin Wu,a   Tzu-Chieh Lin,a   Kuo-Hao Lua  and  Kun-Shian Lina  

* Corresponding authors

a Department of Chemistry, National Dong-Hwa University, Hualien, Taiwan
E-mail: dftai@mail.ndhu.edu.tw
Fax: +886-3-8633570
Tel: +886-3-86335709

Abstract

A quantitative method using artificial antibody to detect creatine kinases was developed. Linear epitope sequences were selected based on an artificial-epitope mapping strategy. Nine different MIPs corresponding to the selected peptides were then fabricated on QCM chips. The subtle conformational changes were also recognized by these chips.

Graphical abstract: Artificial-epitope mapping for CK-MB assay

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Article information

DOI
https://doi.org/10.1039/C0AN00919A
Article type
Communication
Submitted
16 Nov 2010
Accepted
14 Apr 2011
First published
26 Apr 2011

Analyst, 2011,136, 2230-2233

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Artificial-epitope mapping for CK-MB assay

D. Tai, Y. Ho, C. Wu, T. Lin, K. Lu and K. Lin, Analyst, 2011, 136, 2230 DOI: 10.1039/C0AN00919A

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