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Issue 10, 2008
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Towards quantitatively reproducible substrates for SERS

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There is a need for a method to facilitate the development of novel, reproducible colloidal surface-enhanced Raman scattering (SERS) substrates to encourage the use of SERS in applied studies. In this study we show for the first time that by using suitably designed SERS experiments in conjunction with multivariate analysis of variance (MANOVA), an objective assessment of colloidal SERS reproducibility can be made. This is demonstrated with the analyte cresyl violet, but could be extended to any analyte of interest for which reproducible SERS data are needed.

Graphical abstract: Towards quantitatively reproducible substrates for SERS

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Article information

09 Jan 2008
11 Jun 2008
First published
25 Jul 2008

Analyst, 2008,133, 1449-1452
Article type

Towards quantitatively reproducible substrates for SERS

R. M. Jarvis, H. E. Johnson, E. Olembe, A. Panneerselvam, M. A. Malik, M. Afzaal, P. O'Brien and R. Goodacre, Analyst, 2008, 133, 1449
DOI: 10.1039/B800340H

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