Issue 8, 2007
From the journal:

Analyst

A handheld device for potential point-of-care screening of cancer†‡

Chi-Chih Kang,ab   Cheng-Chung Chang,§a   Ta-Chau Chang,*a   Li-Jen Liao,c   Pei-Jen Lou,c   Wenjun Xied  and  Edward S. Yeungd  

* Corresponding authors

a Institute of Atomic and Molecular Sciences, Academia Sinica, P.O. Box 23-166, Taipei, Taiwan 106, Republic of China
E-mail: tcchang@po.iams.sinica.edu.tw

b Taiwan International Graduate Program and Department of Chemistry, National Tsing-Hua University and Academia Sinica, Taiwan, Republic of China

c Department of Otolaryngology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, Republic of China

d Ames Laboratory-USDOE and Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA

Abstract

A simple handheld device based on the fluorescence analysis of 3,6-bis(1-methyl-4-vinylpyridinium)carbazole diiodide (BMVC) stained cells was established for routine screening and potentially for early detection of cancer cells at extremely low cost. Flow cytometry assay further supported the utility of this simple device, where a preliminary study of tissue biopsy showed highly encouraging results.

Graphical abstract: A handheld device for potential point-of-care screening of cancer

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Article information

DOI
https://doi.org/10.1039/B617733F
Article type
Paper
Submitted
05 Dec 2006
Accepted
29 May 2007
First published
08 Jun 2007

Analyst, 2007,132, 745-749

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A handheld device for potential point-of-care screening of cancer

C. Kang, C. Chang, T. Chang, L. Liao, P. Lou, W. Xie and E. S. Yeung, Analyst, 2007, 132, 745 DOI: 10.1039/B617733F

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