Quantitative and qualitative analysis of saframycins. Polarographic and voltammetric behaviour and direct polarographic determination of saframycin A in fermentation broth and the high-performance liquid chromatographic determination of various saframycins

Abstract

The polarographic and voltammetric behaviour of various saframycins has been studied. The scope and limitations of their individual and simultaneous determination and the direct determination of saframycin A in fermentation broth, as compared with results obtained using an HPLC method which allows separation of complex mixtures, are discussed.