Issue 1272, 1982

Gas-chromatographic determination of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (methyl-CCNU). Part I. Cyclisation to a substituted aminooxazoline

Abstract

Methods for the gas-chromatographic determination of methyl-CCNU employing cyclisation to the substituted aminooxazoline have been explored. These procedures were found to be unsatisfactory for the determination of the drug in body fluids.

Article information

Article type
Paper

Analyst, 1982,107, 301-306

Gas-chromatographic determination of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (methyl-CCNU). Part I. Cyclisation to a substituted aminooxazoline

B. Caddy and O. R. Idowu, Analyst, 1982, 107, 301 DOI: 10.1039/AN9820700301

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