Issue 1165, 1973

Molecular interaction errors in phase-solubility analysis

Abstract

Results are presented for the assay by phase-solubility analysis of ibufenac (4-isobutylphenylacetic acid) and of saccharin in the presence of various impurities. The results for impurities obtained for ibufenac mixtures were almost twice those expected, while those for saccharin mixtures were normal. From a consideration of these results, the effect of compound formation by molecular interaction is discussed.

Article information

Article type
Paper

Analyst, 1973,98, 293-296

Molecular interaction errors in phase-solubility analysis

D. T. Burns, J. B. Gallagher, R. J. Stretton and J. S. Wragg, Analyst, 1973, 98, 293 DOI: 10.1039/AN9739800293

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