Issue 54, 2025, Issue in Progress

Exploring the versatility of heterocyclic compounds containing nitrogen atoms (triazoles): a comprehensive review

Abstract

Heterocyclic compounds are cyclic compounds with atoms from at least two different elements in their ring. They play vital roles in regulating biochemical processes in living systems that involve hormones, enzymes, and genetic materials. Among the heterocyclic compounds, triazoles have a fascinating structure that comprises three nitrogen atoms and two carbon atoms. Generally, they are divided into two type of isomers, namely, 1,2,3-triazoles and 1,2,4-triazoles, representing a diverse and essential class of molecules in organic chemistry. Their immense applications in pharmaceutical chemistry and agrochemistry make them vital for humankind. This review is a perfect blend for the researchers and practitioners seeking to explore the versatility, functional diversity, and synthetic methodology of 1,2,3-triazoles and 1,2,4-triazoles from various carbon and nitrogen sources.

Graphical abstract: Exploring the versatility of heterocyclic compounds containing nitrogen atoms (triazoles): a comprehensive review

Transparent peer review

To support increased transparency, we offer authors the option to publish the peer review history alongside their article.

View this article’s peer review history

Article information

Article type
Review Article
Submitted
24 Sep 2025
Accepted
10 Nov 2025
First published
24 Nov 2025
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2025,15, 46243-46263

Exploring the versatility of heterocyclic compounds containing nitrogen atoms (triazoles): a comprehensive review

M. Akram and R. Tamminana, RSC Adv., 2025, 15, 46243 DOI: 10.1039/D5RA07255G

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements