Cycloaddition and functionalization reactions involving tropone

Abstract

Tropones are valuable moieties in the synthesis of natural products and bioactive molecules. Tropones have also emerged as fascinating synthetic partners for various (4 + 2)-, (4 + 6)-, (6 + 3)-, (6 + 4)-, (6 + 6)-, (8 + 2)-, and (8 + 3)-cycloaddition reactions as well as functionalization reactions. This review highlights various cycloaddition and functionalization reactions involving tropone building blocks reported since 2014.