Issue 20, 2025

Recent advances in the synthesis of 3,4-fused tricyclic indoles

Abstract

The 3,4-fused tricyclic indole framework is a key structural motif in numerous bioactive natural products and pharmaceuticals, thus, it has drawn much attention in synthetic organic chemistry. Synthetic organic chemists have expended substantial effort in developing efficient methods for constructing this privileged molecular framework. In this review, we highlight the advances made in this area, particularly since 2018.

Graphical abstract: Recent advances in the synthesis of 3,4-fused tricyclic indoles

Article information

Article type
Review Article
Submitted
04 Feb 2025
Accepted
14 Apr 2025
First published
16 Apr 2025
This article is Open Access
Creative Commons BY-NC license

Org. Biomol. Chem., 2025,23, 4808-4827

Recent advances in the synthesis of 3,4-fused tricyclic indoles

T. Nemoto, S. Harada, T. Kuribara and S. Harada, Org. Biomol. Chem., 2025, 23, 4808 DOI: 10.1039/D5OB00202H

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