Tunable stereoselectivity in a wireless electrochemical microreactor using natural chiral ionic liquids

Abstract

A single drop of a natural chiral ionic liquid (NCIL) serves as a wireless electrochemical microreactor for enantioselective synthesis. This system yields high selectivity (>90% ee) and demonstrates dynamic stereocontrol, where the enantiomeric excess is directly modulated by the external electric field. This catalyst-free strategy introduces a new paradigm for sustainable, tunable asymmetric reactions.