Palladium-catalyzed amination oxidation of electron-rich olefins in green media

Abstract

A palladium-catalyzed amination oxidation of electron-rich olefins with anilines under air at room temperature in ionic liquids was accomplished. Herein, H₂O₂ serves as the oxidant and the oxygen source of the carbonyl group. Notably, this new approach provides a practical and straightforward route to access a broad range of privileged amino acid structures with good yields and excellent regioselectivities. Significantly, internal olefins were also compatible with this transformation.