Ru(ii)-catalyzed stereoselective C(7)–H α-fluoroalkenylation of indolines

Abstract

An efficient method for a ruthenium(II)-catalyzed stereoselective C(7)–H α-fluoroalkenylation of indolines is described. The protocol exhibits good functional group compatibility. The corresponding C7 fluoroalkenylated indolines can be obtained in moderate to excellent yields under mild and convenient conditions. Furthermore, two products synthesized using this method show antibacterial activity against Staphylococcus aureus.