We report the first competitive aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor featuring a fluorogenic binding response and nanomolar affinity (KD), enabling real-time screening of non-fluorescent inhibitors with high cellular compatibility and no observed toxicity.
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S. Ghosh, S. Ghosh, A. Majee, S. Sengupta, S. Mukherjee, B. Roy, R. Das and A. Mukherjee, Chem. Commun., 2025, 61, 16070 DOI: 10.1039/D5CC03947A
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