In this work, a wide range of bridged eight-membered oxygen heterocycles have been constructed through a novel palladium-catalyzed [4 + 4] cycloaddition of 2-pyrones with 2-alkylidenetrimethylene carbonates. The reaction demonstrated a broad substrate scope and afforded the products in good yields with excellent stereoselectivities.
![Graphical abstract: Palladium-catalyzed [4 + 4] cycloaddition of 2-pyrones with 2-alkylidenetrimethylene carbonates: access to bridged eight-membered oxygen heterocycles](/en/Image/Get?imageInfo.ImageType=GA&imageInfo.ImageIdentifier.ManuscriptID=D4QO00329B&imageInfo.ImageIdentifier.Year=2024)
H. Lin, B. Mao, B. Han, J. Luo, Y. Ge, X. Zhang, C. Wang, H. Guo and C. Yuan, Org. Chem. Front., 2024, Advance Article , DOI: 10.1039/D4QO00329B
To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.
If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.
If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.
Read more about how to correctly acknowledge RSC content.
Please wait while we load your content...
