Issue 4, 2024
From the journal:

Organic Chemistry Frontiers

An aminobenzannulation reaction of a propargylic ester and isocyanides to access multi-functionalized aryl amine derivatives†

Zihan Ni,‡a   Jie Hu,‡a   Kun Yin, ORCID logo *b   Tianfang Chen,a   Xiangning Li,a   Lei Cui,*a   Chunju Li ORCID logo c  and  Jian Li ORCID logo *ad  

* Corresponding authors

a Department of Chemistry, College of Sciences, Shanghai University, Shanghai 200444, P. R. China
E-mail: cuilei@shu.edu.cn, lijian@shu.edu.cn

b Anhui Province Key Laboratory for Degradation and Monitoring of Pollution of the Environment, School of Chemistry & Materials Engineering Fuyang Normal University, Fuyang, Anhui 236037, P. R. China
E-mail: yk0309403@163.com

c Tianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin 300387, P. R. China

d School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, P. R. China

Abstract

An aminobenzannulation of two molecular isocyanides and a propargylic ester has been reported. This reaction involves sequential annulation and rearrangement processes, providing efficient access to multi-substituted aniline and naphthylamine derivatives.

Graphical abstract: An aminobenzannulation reaction of a propargylic ester and isocyanides to access multi-functionalized aryl amine derivatives

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/D3QO02011H
Article type
Research Article
Submitted
06 Dec 2023
Accepted
28 Dec 2023
First published
29 Dec 2023

Org. Chem. Front., 2024,11, 1192-1197

Permissions

Request permissions

An aminobenzannulation reaction of a propargylic ester and isocyanides to access multi-functionalized aryl amine derivatives

Z. Ni, J. Hu, K. Yin, T. Chen, X. Li, L. Cui, C. Li and J. Li, Org. Chem. Front., 2024, 11, 1192 DOI: 10.1039/D3QO02011H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements