Synthesis of 1,2,4-diazaphospholes via base-promoted cyclization reaction of hydrazonoyl chlorides and [Bu4N][P(SiCl3)2]

Abstract

Aromatic 1,2,4-diazaphospholes featuring distinct hybrid-mode nitrogen atoms (N(λ³σ²), N(λ³σ³)) and low-valent phosphorus atoms (λ³σ²) exhibited the characteristic of serving as unique hybrid ligands. This study presented a one-pot reaction involving the base-promoted stepwise cyclization of hydrazonoyl chlorides and [Bu₄N][P(SiCl₃)₂] to yield 1,2,4-diazaphospholes, providing an effective method for synthesizing such compounds.